Diana quickly regained her sanity and was taken out of the mental hospital's care. She immediately noted the absence of Barbara and set out to locate her. However, when she arrived at Empire Enterprises, she was greeted only by Doctor Cyber. Cale set Team Poison onto Wonder Woman once again, and Colonel Poison managed to shoot Diana through the chest. Diana and Steve quickly overcame their forces and followed Veronica Cale and Cheetah to a gateway that led to Themyscira. Wonder Woman and Cheetah fought, and a drop of Diana's blood fell onto the gateway which opened the portal to Ares' prison beneath Themyscira. Phobos and Deimos, whom Cale had turned into dogs with the help of Circe, entered the portal, along with Diana and Veronica Cale. Veronica found her daughter beside Ares.
“Of course I wouldn’t expect Miss Roubicek to understand all this,” Marston wrote Gaines. “After all I have devoted my entire life to working out psychological principles. Miss R. has been in comics only 6 months or so, hasn’t she? And never in psychology.” But “the secret of woman’s allure,” he told Gaines, is that “women enjoy submission—being bound.”
The Diana Prince alias also played an important role after the events of Infinite Crisis. Wonder Woman was broadcast worldwide killing a villain named Maxwell Lord, as he was mind controlling Superman into killing Batman. When Wonder Woman caught him in her lasso, demanding to know how to stop Superman, Maxwell revealed that the only way to stop him was to kill Lord, so as a last resort Diana snapped his neck. To recover from the trauma of killing another person, the Amazon went into a self-imposed exile for one year. On her return to public life, Diana realized that her life as a full-time celebrity superhero and ambassador had kept her removed from humanity. Because of this she assumed the persona of Diana Prince and became an agent at the Department of Metahuman Affairs. During a later battle with the witch Circe, a spell was placed on Diana leaving her powerless when not in the guise of Wonder Woman.
As Hippolyta was still a clay statue, Diana was forced to take the Amazon throne, at least until she could find a way to turn her mother back to normal. At the same time, the Justice League had discovered strange environmental events that had destroyed small villages around the world, leaving only vegetation behind. Furious, Wonder Woman attacked Swamp Thing, accusing him of causing such devastation, while Swamp Thing claimed innocence. Aquaman defused the situation before it could escalate any further. Later, Wonder Woman returned to Themyscira, only to discover Hippolyta's statue had crumbled. On a training session, Clark asked Diana if she wanted to talk about her recent experiences, but Diana replied that, as queen, grief is not a luxury she could afford. Later, Diana was called for a meeting by the Amazon council, which forced a choice on her: become permanent Queen or abdicate the throne. Before the discussion could continue, the island was attacked by Stymphalian Birds, Ares’ pets who were now drawn to Diana as the God of War. Accepting her new responsibilities, Diana successfully defended Themyscira.
Not long after this, Athena sensed a dark destiny for the gods amidst the cosmic mechanations of Alexander Luthor Jr.. In the crisis created by his chaos, Diana was forced to kill Maxwell Lord, and incurred the ire of the world's public. The U.S. government responded by mobilizing against Themyscira, and Diana realized that as long as she was a target, the Amazons would never be safe. Diana prayed to the gods to take the Amazons to safety, but got more than she bargained for. On Olympus, she pleaded against Athena's decision to remove the gods from Earth's affairs. Regardless, the gods departed, leaving Diana bereft of family and faith.